Heat Shock Protein-Derived T-Cell Epitopes Contribute to Autoimmune Inflammation in Pediatric Crohn's Disease

Gisella L. Puga Yung; Meredith Fidler; Erika Albani; Naomi Spermon; Gijs Teklenburg; Robert Newbury; Nicole Schechter; Theo van den Broek; Berent Prakken; Rosario Billetta; Ranjan Dohil; Salvatore Albani

doi:10.1371/journal.pone.0007714

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Open Access

Peer-reviewed

Research Article

Heat Shock Protein-Derived T-Cell Epitopes Contribute to Autoimmune Inflammation in Pediatric Crohn's Disease

Gisella L. Puga Yung,

Current address: University Hospital Geneva, Department of Internal Medicine, Service of Immunology and Allergy, Geneva, Switzerland

Affiliations Department of Medicine/Pediatrics, University of California San Diego, La Jolla, California, United States of America, Department of Immunology, Institute of Biomedical Sciences (ICBM), School of Medicine University of Chile, Santiago, Chile, EUREKA Institute for Translational Medicine, Siracusa, Italy
⨯
Meredith Fidler,

Affiliation Department of Medicine/Pediatrics, University of California San Diego, La Jolla, California, United States of America
⨯
Erika Albani,

Affiliations Department of Medicine/Pediatrics, University of California San Diego, La Jolla, California, United States of America, EUREKA Institute for Translational Medicine, Siracusa, Italy
⨯
Naomi Spermon,

Affiliations Department of Medicine/Pediatrics, University of California San Diego, La Jolla, California, United States of America, EUREKA Institute for Translational Medicine, Siracusa, Italy
⨯
Gijs Teklenburg,

Affiliations Department of Medicine/Pediatrics, University of California San Diego, La Jolla, California, United States of America, EUREKA Institute for Translational Medicine, Siracusa, Italy
⨯
Robert Newbury,

Affiliation Department of Medicine/Pediatrics, University of California San Diego, La Jolla, California, United States of America
⨯
Nicole Schechter,

Affiliation Arizona Arthritis Center, University of Arizona, Tucson, Arizona, United States of America
⨯
Theo van den Broek,

Affiliation Arizona Arthritis Center, University of Arizona, Tucson, Arizona, United States of America
⨯
Berent Prakken,

Affiliation EUREKA Institute for Translational Medicine, Siracusa, Italy
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Rosario Billetta,

Affiliation EUREKA Institute for Translational Medicine, Siracusa, Italy
⨯
Ranjan Dohil,

Affiliation Department of Medicine/Pediatrics, University of California San Diego, La Jolla, California, United States of America
⨯
Salvatore Albani

* E-mail: salbani@arthritis.arizona.edu

Affiliations Arizona Arthritis Center, University of Arizona, Tucson, Arizona, United States of America, EUREKA Institute for Translational Medicine, Siracusa, Italy
⨯

Heat Shock Protein-Derived T-Cell Epitopes Contribute to Autoimmune Inflammation in Pediatric Crohn's Disease

Gisella L. Puga Yung,
Meredith Fidler,
Erika Albani,
Naomi Spermon,
Gijs Teklenburg,
Robert Newbury,
Nicole Schechter,
Theo van den Broek,
Berent Prakken,
Rosario Billetta

Published: November 2, 2009
https://doi.org/10.1371/journal.pone.0007714

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