Thrombospondin-1-N-Terminal Domain Induces a Phagocytic State and Thrombospondin-1-C-Terminal Domain Induces a Tolerizing Phenotype in Dendritic Cells

Adi Tabib; Alon Krispin; Uriel Trahtemberg; Inna Verbovetski; Mario Lebendiker; Tsafi Danieli; Dror Mevorach

doi:10.1371/journal.pone.0006840

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Research Article

Thrombospondin-1-N-Terminal Domain Induces a Phagocytic State and Thrombospondin-1-C-Terminal Domain Induces a Tolerizing Phenotype in Dendritic Cells

Adi Tabib ,

* E-mail: mevorachd@hadassah.org.il

Affiliation The Laboratory for Cellular and Molecular Immunology, Rheumatology Research Unit, and The Protein Expression and Protein Purification Facilities, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel
⨯
Alon Krispin ,

* E-mail: mevorachd@hadassah.org.il

Affiliation The Laboratory for Cellular and Molecular Immunology, Rheumatology Research Unit, and The Protein Expression and Protein Purification Facilities, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel
⨯
Uriel Trahtemberg,

Affiliation The Laboratory for Cellular and Molecular Immunology, Rheumatology Research Unit, and The Protein Expression and Protein Purification Facilities, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel
⨯
Inna Verbovetski,

Affiliation The Laboratory for Cellular and Molecular Immunology, Rheumatology Research Unit, and The Protein Expression and Protein Purification Facilities, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel
⨯
Mario Lebendiker,

Affiliation Wolfson Centre for Applied Structural Biology, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel
⨯
Tsafi Danieli,

Affiliation Wolfson Centre for Applied Structural Biology, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel
⨯
Dror Mevorach

Affiliation The Laboratory for Cellular and Molecular Immunology, Rheumatology Research Unit, and The Protein Expression and Protein Purification Facilities, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel
⨯

Thrombospondin-1-N-Terminal Domain Induces a Phagocytic State and Thrombospondin-1-C-Terminal Domain Induces a Tolerizing Phenotype in Dendritic Cells

Adi Tabib,
Alon Krispin,
Uriel Trahtemberg,
Inna Verbovetski,
Mario Lebendiker,
Tsafi Danieli,
Dror Mevorach

Published: August 31, 2009
https://doi.org/10.1371/journal.pone.0006840

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