Fetal and Neonatal Nicotine Exposure in Wistar Rats Causes Progressive Pancreatic Mitochondrial Damage and Beta Cell Dysfunction

Open Access

Peer-reviewed

Research Article

Jennifer E. Bruin,

Affiliation Reproductive Biology Division, Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada
⨯
Maria A. Petre,

Affiliation Reproductive Biology Division, Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada
⨯
Sandeep Raha,

Affiliation Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
⨯
Katherine M. Morrison,

Affiliation Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
⨯
Hertzel C. Gerstein,

Affiliation Department of Medicine, McMaster University, Hamilton, Ontario, Canada
⨯
Alison C. Holloway

* E-mail: hollow@mcmaster.ca

Affiliation Reproductive Biology Division, Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada
⨯

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Mitochondria
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Insulin
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Nicotine
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Glucose
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Nicotine replacement therapy
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Animal models
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Pancreas
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Reactive oxygen species
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