Evaluating the potential of Vitamin D and curcumin to alleviate inflammation and mitigate the progression of osteoarthritis through their effects on human chondrocytes: A proof-of-concept investigation

Rajashree Patnaik; Sumbal Riaz; Bala Mohan Sivani; Shemima Faisal; Nerissa Naidoo; Manfredi Rizzo; Yajnavalka Banerjee

doi:10.1371/journal.pone.0290739

Loading metrics

Open Access

Peer-reviewed

Research Article

Evaluating the potential of Vitamin D and curcumin to alleviate inflammation and mitigate the progression of osteoarthritis through their effects on human chondrocytes: A proof-of-concept investigation

Rajashree Patnaik,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Writing – original draft

Affiliation College of Medicine and Health Sciences, Mohammed Bin Rashid University of Medicine, and Health Sciences (MBRU), Dubai, United Arab Emirates
⨯
Sumbal Riaz,

Roles Data curation, Methodology

Affiliation College of Medicine and Health Sciences, Mohammed Bin Rashid University of Medicine, and Health Sciences (MBRU), Dubai, United Arab Emirates
⨯
Bala Mohan Sivani,

Roles Data curation, Methodology

Current address: Department of Molecular Biology, Lund University, Lund, Sweden

Affiliation College of Medicine and Health Sciences, Mohammed Bin Rashid University of Medicine, and Health Sciences (MBRU), Dubai, United Arab Emirates
⨯
Shemima Faisal,

Roles Data curation

Affiliation College of Medicine and Health Sciences, Mohammed Bin Rashid University of Medicine, and Health Sciences (MBRU), Dubai, United Arab Emirates
⨯
Nerissa Naidoo,

Roles Formal analysis, Funding acquisition, Supervision, Validation

Affiliation College of Medicine and Health Sciences, Mohammed Bin Rashid University of Medicine, and Health Sciences (MBRU), Dubai, United Arab Emirates
⨯
Manfredi Rizzo ,

Roles Formal analysis

* E-mail: yajnavalka.banerjee@mbru.ac.ae (YB); manfredi.rizzo@unipa.it (MR)

Affiliation Department of Health Promotion, Mother and Child Care, Internal Medicine, and Medical Specialties (Promise), University of Palermo, Palermo, Italy
⨯
Yajnavalka Banerjee

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: yajnavalka.banerjee@mbru.ac.ae (YB); manfredi.rizzo@unipa.it (MR)

Affiliations College of Medicine and Health Sciences, Mohammed Bin Rashid University of Medicine, and Health Sciences (MBRU), Dubai, United Arab Emirates, Centre for Medical Education, University of Dundee, Dundee, United Kingdom

https://orcid.org/0000-0002-7546-8893

⨯

Evaluating the potential of Vitamin D and curcumin to alleviate inflammation and mitigate the progression of osteoarthritis through their effects on human chondrocytes: A proof-of-concept investigation

Rajashree Patnaik,
Sumbal Riaz,
Bala Mohan Sivani,
Shemima Faisal,
Nerissa Naidoo,
Manfredi Rizzo,
Yajnavalka Banerjee

Published: December 29, 2023
https://doi.org/10.1371/journal.pone.0290739

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Vitamin D
Is the Subject Area "Vitamin D" applicable to this article?

Thanks for your feedback.
Chondrocytes
Is the Subject Area "Chondrocytes" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Osteoarthritis
Is the Subject Area "Osteoarthritis" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Knee joints
Is the Subject Area "Knee joints" applicable to this article?

Thanks for your feedback.
Cartilage
Is the Subject Area "Cartilage" applicable to this article?

Thanks for your feedback.
Pain
Is the Subject Area "Pain" applicable to this article?

Thanks for your feedback.