Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis

Fanlei Hu; Yingni Li; Li Zheng; Lianjie Shi; Hongjiang Liu; Xuewu Zhang; Huaqun Zhu; Sumei Tang; Lei Zhu; Liling Xu; Yuqin Yang; Zhanguo Li

doi:10.1371/journal.pone.0100266

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Open Access

Peer-reviewed

Research Article

Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis

Fanlei Hu ,

Contributed equally to this work with: Fanlei Hu, Yingni Li

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Yingni Li ,

Contributed equally to this work with: Fanlei Hu, Yingni Li

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Li Zheng,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Lianjie Shi,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Hongjiang Liu,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Xuewu Zhang,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Huaqun Zhu,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Sumei Tang,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Lei Zhu,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Liling Xu,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Yuqin Yang,

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯
Zhanguo Li

* E-mail: li99@bjmu.edu.cn

Affiliation Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China
⨯

Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis

Fanlei Hu,
Yingni Li,
Li Zheng,
Lianjie Shi,
Hongjiang Liu,
Xuewu Zhang,
Huaqun Zhu,
Sumei Tang,
Lei Zhu,
Liling Xu

Published: June 17, 2014
https://doi.org/10.1371/journal.pone.0100266

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Inflammation
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Toll-like receptors
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Inflammatory diseases
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Fibroblasts
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