Complement C3 Deficiency Attenuates Chronic Hypoxia-Induced Pulmonary Hypertension in Mice

Open Access

Peer-reviewed

Research Article

Eileen M. Bauer,

Affiliation Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Han Zheng,

Affiliation Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Suzy Comhair,

Affiliations Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Serpil Erzurum,

Affiliations Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯
Timothy R. Billiar,

Affiliation Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Philip M. Bauer

* E-mail: bauerpm@upmc.edu

Affiliations Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Medical hypoxia
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Mouse models
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Fibrin
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Platelet activation
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Complement system
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Platelets
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Pulmonary hypertension
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Hemorrhage
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