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Referee comments: Referee 2

Posted by PLOS_ONE_Group on 04 Apr 2008 at 16:29 GMT

Referee 2's review:

This is an interesting manuscript demonstrating that efficient electroporation of cells in the SVZ that resemble radial glial cells is possible even at postnatal ages. Similar approaches have so far only employed to developing embryos. The electroporation method will greatly facilitate the study of neurogenesis in the SVZ and provides great advantages compared to virus based systems because simple plasmid vectors can be electroporated.

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N.B. These are the comments made by the referee when reviewing an earlier version of this paper. Prior to publication the manuscript has been revised in light of these comments and to address other editorial requirements.