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Open Access
Peer-reviewed
Research Article
Copy Number Variations in Alternative Splicing Gene Networks Impact Lifespan
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Joseph T. Glessner,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Albert Vernon Smith,
Affiliations Icelandic Heart Association, Heart Preventive Clinic and Research Institute, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland
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Saarene Panossian,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Cecilia E. Kim,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Nagahide Takahashi,
Affiliation Laboratory of Molecular Neuropsychiatry, Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America
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Kelly A. Thomas,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Fengxiang Wang,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Kallyn Seidler,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Tamara B. Harris,
Affiliation Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
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Lenore J. Launer,
Affiliation Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
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Brendan Keating,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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John Connolly,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Patrick M. A. Sleiman,
Affiliation Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Joseph D. Buxbaum,
Affiliation Laboratory of Molecular Neuropsychiatry, Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America
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Struan F. A. Grant,
Affiliations Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
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Vilmundur Gudnason,
Affiliations Icelandic Heart Association, Heart Preventive Clinic and Research Institute, Kopavogur, Iceland, University of Iceland, Reykjavik, Iceland
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Hakon Hakonarson
* E-mail: hakonarson@chop.edu
Affiliations Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Division of Genetics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
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Copy Number Variations in Alternative Splicing Gene Networks Impact Lifespan
- Joseph T. Glessner,
- Albert Vernon Smith,
- Saarene Panossian,
- Cecilia E. Kim,
- Nagahide Takahashi,
- Kelly A. Thomas,
- Fengxiang Wang,
- Kallyn Seidler,
- Tamara B. Harris,
- Lenore J. Launer
- Published: January 30, 2013
- https://doi.org/10.1371/journal.pone.0053846