In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/Luciferase Reporter Construct

Fabio Franco Stellari; Valentina Franceschi; Antonio Capocefalo; Marcello Ronchei; Fabrizio Facchinetti; Gino Villetti; Gaetano Donofrio

doi:10.1371/journal.pone.0039716

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Peer-reviewed

Research Article

In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/Luciferase Reporter Construct

Fabio Franco Stellari,

Affiliations Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Università di Parma, Parma, Italy, Chiesi Farmaceutici S.p.A, Parma, Italy
⨯
Valentina Franceschi,

Affiliation Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Università di Parma, Parma, Italy
⨯
Antonio Capocefalo,

Affiliation Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Università di Parma, Parma, Italy
⨯
Marcello Ronchei,

Affiliation Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Università di Parma, Parma, Italy
⨯
Fabrizio Facchinetti,

Affiliation Chiesi Farmaceutici S.p.A, Parma, Italy
⨯
Gino Villetti,

Affiliation Chiesi Farmaceutici S.p.A, Parma, Italy
⨯
Gaetano Donofrio

* E-mail: gaetano.donofrio@unipr.it

Affiliation Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Università di Parma, Parma, Italy
⨯

In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/Luciferase Reporter Construct

Fabio Franco Stellari,
Valentina Franceschi,
Antonio Capocefalo,
Marcello Ronchei,
Fabrizio Facchinetti,
Gino Villetti,
Gaetano Donofrio

Published: June 28, 2012
https://doi.org/10.1371/journal.pone.0039716

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A convenient non-invasive in vivo test system for gene activation

Posted by kaltebe on 04 Jul 2012 at 15:20 GMT

This paper is interesting for the convenient transient transgenization approach combined with in vivo imaging of activation of the luciferase reporter. This allows convenient study of in vivo gene regulation.

No competing interests declared.

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In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/Luciferase Reporter Construct

In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/Luciferase Reporter Construct

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A convenient non-invasive in vivo test system for gene activation

Posted by kaltebe on 04 Jul 2012 at 15:20 GMT