About the Authors

Thea Bommer

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany

Maria Knierim

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Cardiothoracic and Vascular Surgery, University Medical Centre Göttingen, Göttingen, Germany

Julia Unsöld

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany

Dominic Riedl

Roles Data curation, Investigation, Methodology, Software

Affiliation Justus-Liebig-University Gießen Medical Clinic I and Campus Kerckhoff Bad Nauheim, Gießen and Bad Nauheim, Germany

Laura Stengel

Roles Investigation, Methodology

Affiliation Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany

Michael Paulus

Roles Investigation, Methodology, Resources

Affiliation Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany

Thomas Körtl

Roles Investigation, Methodology, Validation

Affiliation Justus-Liebig-University Gießen Medical Clinic I and Campus Kerckhoff Bad Nauheim, Gießen and Bad Nauheim, Germany

Norman Liaw

Roles Conceptualization, Investigation

Affiliation Institute of Pharmacology and Toxicology, University Medical Centre Göttingen, Göttingen, Germany

Lars S. Maier

Roles Project administration, Resources, Supervision, Writing – review & editing

Affiliation Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany

Katrin Streckfuss-Bömeke

Roles Conceptualization, Data curation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

Affiliations Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany, Clinic for Cardiology and Pneumology, Georg-August University Göttingen, DZHK (German Centre for Cardiovascular Research), Partner Site Göttingen, Göttingen, Germany

Samuel Sossalla

Contributed equally to this work with: Samuel Sossalla, Steffen Pabel

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Justus-Liebig-University Gießen Medical Clinic I and Campus Kerckhoff Bad Nauheim, Gießen and Bad Nauheim, Germany

Steffen Pabel

Contributed equally to this work with: Samuel Sossalla, Steffen Pabel

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – original draft

spabel@mgh.harvard.edu

Affiliations Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany, Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States of America

Competing Interests

STS received speakers/consulting honoraria from Astra Zeneca, Novartis, Berlin-Chemie, DAIICHI SANKYO, Bristol-Myers-Squibb, Pfizer, Boehringer Ingelheim, Lilly. The other authors have declared that no competing interests exist. This does not alter our adherence to PLOS ONE policies on sharing data and materials.