About the Authors

Shuji Uno

Contributed equally to this work with: Shuji Uno, Shuichi Midorikawa

Roles Conceptualization, Data curation, Methodology, Project administration, Writing – original draft, Writing – review & editing

shuji.uno@bms.com

Affiliation Japan Medical-Hematology, Bristol-Myers Squibb K.K., Tokyo, Japan

Shuichi Midorikawa

Contributed equally to this work with: Shuji Uno, Shuichi Midorikawa

Roles Conceptualization, Data curation, Methodology, Project administration, Writing – review & editing

Affiliation Biometrics and Data Sciences, Bristol-Myers Squibb K.K., Tokyo, Japan

Kei Inoue

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation SUSMED, Inc, Tokyo, Japan

Daisuke Ichikawa

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation SUSMED, Inc, Tokyo, Japan

Tomoki Ito

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation First Department of Internal Medicine, Kansai Medical University, Osaka, Japan

Junya Kuroda

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

Kenshi Suzuki

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Hematology, Japan Red Cross Medical Center, Tokyo, Japan

Competing Interests

S.U. and S.M. are employees of Bristol Myers Squibb K.K. and stockholders of Bristol Myers Squibb. K.I. and D.I. are employees of SUSMED Inc. These do not alter the authors’ adherence to PLOS ONE policies on sharing data and materials. T.I. reports study funding from Bristol Myers Squibb K.K. and honoraria from AbbVie, AstraZeneca, Bristol Myers Squibb, Chugai, CSL Behring, Novartis, Sanofi, and Takeda. J.K. reports grants or contracts from Asahi Kasei, Bristol Myers Squibb, Chugai Pharmaceutical, Daiichi Sankyo, Eizai, Fujimoto Pharmaceutical, Kyowa Kirin, Nippon Shinyaku, Ono Pharmaceutical, Otsuka Pharmaceutical, Sanofi, Shionogi, Sumitomo Pharmaceutical, Takeda Pharmaceutical, and Taiho Pharmaceutical; consulting fees from Bristol Myers Squibb and Janssen Pharmaceutical; and payments or honoraria from Bristol Myers Squibb, Janssen Pharmaceutical, Ono Pharmaceutical, and Sanofi. K.S. reports honoraria from Abbvie, Amgen, Bristol Myers Squibb, Janssen, Novartis, ONO, Sanofi, and Takeda; consulting fees from Amgen, Bristol Myers Squibb and Takeda; and research funding from Bristol Myers Squibb.