Occurrence of a novel cleavage site for cathepsin G adjacent to the polybasic sequence within the proteolytically sensitive activation loop of the SARS-CoV-2 Omicron variant: The amino acid substitution N679K and P681H of the spike protein

Open Access

Peer-reviewed

Research Article

About the Authors

Zhadyra Mustafa

Roles Software, Visualization, Writing – original draft

Affiliation Department of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan, Kazakhstan Republic

Hubert Kalbacher

Roles Formal analysis, Investigation, Methodology, Software, Validation

Affiliation Institute of Clinical Anatomy and Cell Analysis, Faculty of Medicine, Eberhard Karls University of Tübingen, Tübingen, Germany

Timo Burster

Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Department of Biology, School of Sciences and Humanities, Nazarbayev University, Nur-Sultan, Kazakhstan Republic

The authors declare no conflict of interest.

SARS CoV 2
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SARS coronavirus
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Amino acid substitution
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Proteases
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Neutrophils
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COVID 19
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Serine proteases
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Host cells
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