About the Authors

Ajay Kesar

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

science@ada.com

Affiliation Ada Health GmbH, Berlin, Germany

Adel Baluch

Roles Data curation

Affiliation Ada Health GmbH, Berlin, Germany

Omer Barber

Roles Data curation

Affiliation Ada Health GmbH, Berlin, Germany

Henry Hoffmann

Roles Funding acquisition, Resources, Supervision, Writing – review & editing

Affiliation Ada Health GmbH, Berlin, Germany

Milan Jovanovic

Roles Data curation

Affiliation Ada Health GmbH, Berlin, Germany

Daniel Renz

Roles Formal analysis, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

Affiliation Ada Health GmbH, Berlin, Germany

Bernard Leon Stopak

Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

Affiliation Ada Health GmbH, Berlin, Germany

Paul Wicks

Roles Conceptualization, Writing – original draft, Writing – review & editing

Affiliation Ada Health GmbH, Berlin, Germany

Stephen Gilbert

Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliations Ada Health GmbH, Berlin, Germany, EKFZ for Digital Health, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany

Competing Interests

This research was funded by Ada Health GmbH and has been conducted using the UK Biobank under application number 34802. All of the authors are or were employees of, contractors for, or hold equity in Ada Health GmbH. AK, AB, OB, HH, MJ, DN, BLS and SG are employees or company directors of Ada Health GmbH and some of the listed authors hold stock options in the company. Ada Health GmbH has received research grant funding from the Bill & Melinda Gates Foundation, Fondation Botnar, the Federal Ministry of Education and Research Germany, the Federal Ministry for Economic Affairs and Energy Germany and the European Union. PW is employed by Wicks Digital Health Ltd, which has received funding from Ada Health, AstraZeneca, Baillie Gifford, Biogen, Bold Health, Camoni, Compass Pathways, Coronna, EIT, Endava, Happify, HealthUnlocked, Inbeeo, Kheiron Medical, Lindus Health, Sano Genetics, Self Care Catalysts, The Learning Corp, The Wellcome Trust, THREAD Research, VeraSci, and Woebot. HH is the topic driver of the AI-based symptom assessment group of the WHO/ITU Focus Group on AI4H (Artificial Intelligence for Health) and SG is a member of the clinical evaluation topic group of the WHO/ITU Focus Group on AI4H. A related patent application is currently pending with the title “System and method for predicting the risk of a patient to develop an atherosclerotic cardiovascular disease” and application number EP21191089.8. This does not alter our adherence to PLOS ONE policies on sharing data and materials.