Machine learning analysis of volatolomic profiles in breath can identify non-invasive biomarkers of liver disease: A pilot study

Jonathan N. Thomas; Joanna Roopkumar; Tushar Patel

doi:10.1371/journal.pone.0260098

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Open Access

Peer-reviewed

Research Article

Machine learning analysis of volatolomic profiles in breath can identify non-invasive biomarkers of liver disease: A pilot study

Jonathan N. Thomas,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Transplantation, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, United States of America
⨯
Joanna Roopkumar,

Roles Investigation

Affiliation Department of Transplantation, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, United States of America
⨯
Tushar Patel

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: patel.tushar@mayo.edu

Affiliation Department of Transplantation, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, United States of America

https://orcid.org/0000-0001-7021-9532

⨯

Machine learning analysis of volatolomic profiles in breath can identify non-invasive biomarkers of liver disease: A pilot study

Jonathan N. Thomas,
Joanna Roopkumar,
Tushar Patel

Published: November 30, 2021
https://doi.org/10.1371/journal.pone.0260098

About the Authors

Jonathan N. Thomas

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Transplantation, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, United States of America

Joanna Roopkumar

Roles Investigation

Affiliation Department of Transplantation, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, United States of America

Tushar Patel

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: patel.tushar@mayo.edu

Affiliation Department of Transplantation, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, United States of America

https://orcid.org/0000-0001-7021-9532

Competing Interests

The authors have declared that no competing interests exist.

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Cirrhosis
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Portal hypertension
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Biomarkers
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Volatile organic compounds
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Machine learning
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Specimen storage
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Liver diseases
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Machine learning algorithms
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