About the Authors

David Zakim

Contributed equally to this work with: David Zakim, Helge Brandberg, Thomas Kahan, Jonas Spaak, Sabine Koch, Carl Johan Sundberg

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

david.zakim@ki.se

Affiliation Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden

Helge Brandberg

Contributed equally to this work with: David Zakim, Helge Brandberg, Thomas Kahan, Jonas Spaak, Sabine Koch, Carl Johan Sundberg

Roles Supervision, Writing – review & editing

Affiliation Division of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Solna, Stockholm County, Sweden

Sami El Amrani

Roles Data curation, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliation Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden

Andreas Hultgren

Roles Data curation, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliation Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden

Natalia Stathakarou

Roles Data curation, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliation Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden

Sokratis Nifakos

Roles Data curation, Resources, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliation Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden

Thomas Kahan

Contributed equally to this work with: David Zakim, Helge Brandberg, Thomas Kahan, Jonas Spaak, Sabine Koch, Carl Johan Sundberg

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Division of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Solna, Stockholm County, Sweden

Jonas Spaak

Contributed equally to this work with: David Zakim, Helge Brandberg, Thomas Kahan, Jonas Spaak, Sabine Koch, Carl Johan Sundberg

Roles Supervision, Writing – review & editing

Affiliation Division of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Solna, Stockholm County, Sweden

Sabine Koch

Contributed equally to this work with: David Zakim, Helge Brandberg, Thomas Kahan, Jonas Spaak, Sabine Koch, Carl Johan Sundberg

Roles Software, Writing – review & editing

Affiliation Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden

Carl Johan Sundberg

Contributed equally to this work with: David Zakim, Helge Brandberg, Thomas Kahan, Jonas Spaak, Sabine Koch, Carl Johan Sundberg

Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

Affiliations Department of Learning, Informatics, Management and Ethics, Medical Management Centre, and Health Informatics Centre, Karolinska Institutet, Stockholm, Sweden, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

Competing Interests

All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: no support from any organization for the submitted work; no financial relationships with any organizations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work. DZ is the sole inventor on US Patent 7,379,885: "A system and method for obtaining, processing and evaluating patient information for diagnosing disease and selecting treatment." This patent has not been maintained and is no longer valid. All copyrights to CLEOS technology, language, images, and knowledge content have been assigned, to Karolinska Institutet, Stockholm, Sweden without compensation and royalty rights to DZ. Karolinska Institutet is a public university and the sole owner of the CLEOS program. Apart from Karolinska Institutet and its subsidiaries, no individuals or companies may be owners or receive royalties or other revenue from use of CLEOS technology, language, images, knowledge content, data, or clinical insights and/or computer algorithms generated from analysis of data acquired by the program. The existing patent to DZ does not affect our adherence to PLOS ONE policies on sharing data.