About the Authors

Hideyasu Yamada

Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

h.yamada@md.tsukuba.ac.jp

Affiliations Faculty of Medicine, Department of Pulmonary Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan, Division of Respiratory Medicine, Hitachi Ltd, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan

Masayuki Nakajima

Roles Data curation

Affiliation Faculty of Medicine, Department of Pulmonary Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan

Masashi Matsuyama

Roles Data curation

Affiliation Faculty of Medicine, Department of Pulmonary Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan

Yuko Morishima

Roles Data curation

Affiliation Faculty of Medicine, Department of Pulmonary Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan

Naoki Arai

Roles Data curation

Affiliation Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Tokaimura, Ibaraki, Japan

Norihito Hida

Roles Data curation

Affiliation Division of Respiratory Medicine, Hitachi Ltd, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan

Taisuke Nakaizumi

Roles Data curation

Affiliation Division of Respiratory Medicine, Hitachi Ltd, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan

Hironori Masuko

Roles Data curation

Affiliation Faculty of Medicine, Department of Pulmonary Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan

Yohei Yatagai

Roles Data curation

Affiliation Division of Respiratory Medicine, Tsukuba Gakuen Hospital, Tsukuba, Ibaraki, Japan

Takefumi Saito

Roles Data curation

Affiliation Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Tokaimura, Ibaraki, Japan

Nobuyuki Hizawa

Roles Methodology, Project administration, Supervision, Validation, Writing – review & editing

Affiliation Faculty of Medicine, Department of Pulmonary Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan

Competing Interests

H.Y. has received lecture fees from AstraZeneca, Sanofi and Boehringer Ingelheim. N. Hizawa is on the GlaxoSmithKline advisory board; has received research support from Astellas, AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Kyorin, MSD, Novartis, and Chugai Pharmaceutical; and has received lecture fees from Astellas, AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Kyorin, MSD, and Novartis. The rest of the authors declare that they have no relevant conflicts of interest. This does not alter our adherence to PLOS ONE policies on sharing data and materials.