About the Authors

Matthew H. McIntyre

Roles Methodology, Writing – original draft

Affiliation 23andMe Inc., Mountain View, California, United States of America

23andMe Research Team

Membership of the 23andMe Research Team is provided in the Acknowledgments.

Affiliation 23andMe Inc., Mountain View, California, United States of America

Achim Kless

Roles Conceptualization, Supervision, Writing – original draft

Kless@gmx.net (AK); Joyce@23andme.com (JT)

Affiliation Grünenthal Innovation, Grünenthal GmbH, Aachen, Germany

Peter Hein

Roles Conceptualization, Methodology, Writing – original draft

Affiliation Grünenthal Innovation, Grünenthal GmbH, Aachen, Germany

Mark Field

Roles Writing – review & editing

Affiliation Grünenthal Innovation, Grünenthal GmbH, Aachen, Germany

Joyce Y. Tung

Roles Supervision

Kless@gmx.net (AK); Joyce@23andme.com (JT)

Affiliation 23andMe Inc., Mountain View, California, United States of America

Competing Interests

This research was conducted by 23andMe and Grünenthal GmbH. All authors are employees of these companies. The commercial affiliation of the authors with both companies does not alter their adherence to PLOS ONE policies on sharing data and materials.