About the Authors

Sven F. Garbade

Roles Data curation, Formal analysis, Software, Writing – review & editing

Affiliation Division of Pediatric Neurology and Metabolic Medicine, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany

Matthias Zielonka

Roles Formal analysis, Writing – review & editing

Affiliation Division of Pediatric Neurology and Metabolic Medicine, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany

Konstantin Mechler

Roles Formal analysis, Writing – review & editing

Affiliation Department of Child and Adolescent Psychiatry and Psychotherapy & Department of Addictive Behavior and Addiction Medicine, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany

Stefan Kölker

Roles Formal analysis, Writing – review & editing

Affiliation Division of Pediatric Neurology and Metabolic Medicine, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany

Georg F. Hoffmann

Roles Formal analysis, Writing – review & editing

Affiliation Division of Pediatric Neurology and Metabolic Medicine, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany

Christian Staufner

Roles Formal analysis, Writing – review & editing

Affiliation Division of Pediatric Neurology and Metabolic Medicine, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany

Eugen Mengel

Roles Formal analysis, Writing – review & editing

Affiliation SphinCS GmbH, Science for LSD, Hochheim, Germany

Markus Ries

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft

markus.ries@uni-heidelberg.de

Affiliations Division of Pediatric Neurology and Metabolic Medicine, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany, Center for Rare Diseases, University Hospital Heidelberg, Heidelberg, Germany, Center for Virtual Patients, Medical Faculty, University of Heidelberg, Heidelberg, Germany

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: SG, SK, and CS have no potential conflicts of interest to declare with respect to the research, authorship, and/or publication of this article. KM has served as investigator in clinical trials conducted by Emalex, Gedeon Richter, Lundbeck, Shire, Sunovion and Teva, plus in European Union funded projects. GFH received lecturing fees from Danone and Takeda. EM has received honoraria and/or consulting fees from Actelion, Alexion, BioMarin, Orphazyme, Sanofi Genzyme, and Shire. MR received consultancy fees or research grants from Alexion, GSK, Oxyrane and Shire. EM is managing partner of SphinCS GmbH, a private clinical research institute, which had research grants from Sanofi Genzyme, Takeda, Alexion, Orphazyme and Idorsia. This does not alter our adherence to PLOS ONE policies on sharing data and materials.