About the Authors

Lilian Otalora

Roles Data curation, Formal analysis, Investigation, Methodology, Validation

Affiliations Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Efren Chavez

Roles Data curation, Formal analysis, Investigation, Validation

Affiliations Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Department of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, Florida, United States of America

Daniel Watford

Roles Data curation, Formal analysis, Investigation, Validation

Affiliation Department of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, Florida, United States of America

Lissett Tueros

Roles Data curation, Formal analysis

Affiliations Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Mayrin Correa

Roles Data curation, Formal analysis, Investigation, Validation

Affiliation Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Viji Nair

Roles Data curation, Formal analysis, Methodology, Resources, Validation, Visualization

Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

Philip Ruiz

Roles Data curation, Formal analysis, Methodology

Affiliations Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Patricia Wahl

Roles Data curation

Affiliations Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Sean Eddy

Roles Formal analysis, Methodology, Validation

Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

Sebastian Martini

Roles Data curation, Formal analysis, Methodology, Validation

Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

Matthias Kretzler

Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation

Affiliation Division of Nephrology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

George W. Burke III

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – review & editing

Affiliations Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Alessia Fornoni

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – review & editing

afornoni@med.miami.edu (AF); smerscher@med.miami.edu (SM)

Affiliations Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Sandra Merscher

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

afornoni@med.miami.edu (AF); smerscher@med.miami.edu (SM)

Affiliations Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Competing Interests

G.W.B., A.F., and S. Merscher. are inventors on pending or issued patents aimed to diagnose or treat proteinuric renal diseases. They stand to gain royalties from their future commercialization. A.F. is Chief Scientific Officer of L&F Health LLC and is consultant for Variant Pharmaceutical. Variant Pharmaceuticals, Inc. has licensed worldwide rights to develop and commercialize hydroxypropyl-beta-cyclodextrin for treatment of kidney disease from L&F Research. A.F. is Chief Scientific Officer for LipoNexT LLC. S. Merscher holds equity interest in L&F Research. Grant funding to support the work has been received by the U Michigan in support of the work performed by M.K. from the National Institute of Health, European Union, Else Kroener Fresenius Foundation, Nephcure Kidney International, Eli Lilly and Goldfinch Bio. These funding bodies did not had influence on study design; collection, analysis, and interpretation of data; writing of the paper; and/or decision to submit for publication. S.E. has declared stock ownership from Thermo Fisher Scientific, Johnson and Johnson and Gilead Sciences and former employment by Thermo Fisher Scientific, Johnson and Johnson. L.O., E.C., D.W., V.N., M.C., P.R., P.W., L.T. have declared no competing interests. Any of the existing conflicts do not alter our adherence to PLOS ONE policies on sharing data and materials.