About the Authors

Jared D. Hoffman

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliations Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America, Department of Pharmacology and Nutritional Science, University of Kentucky, Lexington, Kentucky, United States of America

Lucille M. Yanckello

Roles Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – review & editing

Affiliations Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America, Department of Pharmacology and Nutritional Science, University of Kentucky, Lexington, Kentucky, United States of America

George Chlipala

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Writing – original draft, Writing – review & editing

Affiliation Research Resources Center, University of Illinois at Chicago, Chicago, Illinois, United States of America

Tyler C. Hammond

Roles Conceptualization, Validation, Writing – review & editing

Affiliations Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America, Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America

Scott D. McCulloch

Roles Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing – review & editing

Affiliation Metabolon Inc., Durham, North Carolina, United States of America

Ishita Parikh

Roles Investigation, Methodology, Supervision, Writing – review & editing

Affiliations Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

Sydney Sun

Roles Formal analysis, Validation, Visualization, Writing – review & editing

Affiliation Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America

Josh M. Morganti

Roles Formal analysis, Investigation, Methodology, Resources, Writing – review & editing

Affiliations Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America, Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America, Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky, United States of America

Stefan J. Green

Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Research Resources Center, University of Illinois at Chicago, Chicago, Illinois, United States of America

Ai-Ling Lin

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

ailing.lin@uky.edu

Affiliations Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America, Department of Pharmacology and Nutritional Science, University of Kentucky, Lexington, Kentucky, United States of America, Department of Neuroscience, University of Kentucky, Lexington, Kentucky, United States of America, F. Joseph Halcomb III, M.D. Department of Biomedical Engineering, University of Kentucky, Lexington, Kentucky, United States of America

Competing Interests

Scott McCulloch is employed by Metabolon Inc. This does not alter our adherence to PLOS ONE policies on sharing data and materials.