Cost and efficacy comparison of prenatal recall and reflex DNA screening for trisomy 21, 18 and 13

Jonathan Paul Bestwick; Nicholas John Wald

doi:10.1371/journal.pone.0220053

Loading metrics

Open Access

Peer-reviewed

Research Article

Cost and efficacy comparison of prenatal recall and reflex DNA screening for trisomy 21, 18 and 13

Jonathan Paul Bestwick ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: j.p.bestwick@qmul.ac.uk

Affiliation Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London Charterhouse Square, London, United Kingdom

http://orcid.org/0000-0002-3088-8616

⨯
Nicholas John Wald

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London Charterhouse Square, London, United Kingdom

http://orcid.org/0000-0003-1676-5908

⨯

Cost and efficacy comparison of prenatal recall and reflex DNA screening for trisomy 21, 18 and 13

Jonathan Paul Bestwick,
Nicholas John Wald

Published: July 25, 2019
https://doi.org/10.1371/journal.pone.0220053

About the Authors

Jonathan Paul Bestwick

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: j.p.bestwick@qmul.ac.uk

Affiliation Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London Charterhouse Square, London, United Kingdom

http://orcid.org/0000-0002-3088-8616

Nicholas John Wald

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London Charterhouse Square, London, United Kingdom

http://orcid.org/0000-0003-1676-5908

Competing Interests

Nicholas J. Wald is director of Logical Medical Systems, which produces software for the interpretation of prenatal screening tests.This does not alter our adherence to PLOS ONE policies on sharing data and materials. The other authors declare no conflict of interest.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Selection markers
Is the Subject Area "Selection markers" applicable to this article?

Thanks for your feedback.
Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.
Reflexes
Is the Subject Area "Reflexes" applicable to this article?

Thanks for your feedback.
DNA analysis
Is the Subject Area "DNA analysis" applicable to this article?

Thanks for your feedback.
Down syndrome
Is the Subject Area "Down syndrome" applicable to this article?

Thanks for your feedback.
Blood
Is the Subject Area "Blood" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.