Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica

Brenda H. Welter; Heather A. Walters; Lesly A. Temesvari

doi:10.1371/journal.pone.0219870

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Peer-reviewed

Research Article

Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica

Brenda H. Welter,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliations Department of Biological Sciences, Clemson University, Clemson, South Carolina, United States of America, Eukaryotic Pathogens Innovations Center (EPIC), Clemson University, Clemson, South Carolina, United States of America
⨯
Heather A. Walters,

Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

Affiliations Department of Biological Sciences, Clemson University, Clemson, South Carolina, United States of America, Eukaryotic Pathogens Innovations Center (EPIC), Clemson University, Clemson, South Carolina, United States of America
⨯
Lesly A. Temesvari

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: LTEMESV@clemson.edu

Affiliations Department of Biological Sciences, Clemson University, Clemson, South Carolina, United States of America, Eukaryotic Pathogens Innovations Center (EPIC), Clemson University, Clemson, South Carolina, United States of America

http://orcid.org/0000-0002-4154-8158

⨯

Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica

Brenda H. Welter,
Heather A. Walters,
Lesly A. Temesvari

Published: March 5, 2020
https://doi.org/10.1371/journal.pone.0219870

About the Authors

Brenda H. Welter

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliations Department of Biological Sciences, Clemson University, Clemson, South Carolina, United States of America, Eukaryotic Pathogens Innovations Center (EPIC), Clemson University, Clemson, South Carolina, United States of America

Heather A. Walters

Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

Lesly A. Temesvari

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: LTEMESV@clemson.edu

http://orcid.org/0000-0002-4154-8158

Competing Interests

The authors have declared that no competing interests exist.

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Lipids
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Proteases
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Lectins
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Entamoeba histolytica
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Immunoprecipitation
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Centrifugation
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Sucrose
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Drug interactions
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