About the Authors

Lilia Turcios

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliations Department of Surgery, Transplant Center, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America, Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America

Eduardo Chacon

Roles Data curation, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Surgery, Transplant Center, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

Catherine Garcia

Roles Data curation, Validation, Writing – review & editing

Affiliation Department of Surgery, Transplant Center, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

Pedro Eman

Roles Data curation, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Surgery, Transplant Center, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

Virgilius Cornea

Roles Methodology, Resources

Affiliations Department of Surgery, Transplant Center, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America, Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America

Jieyun Jiang

Roles Conceptualization, Validation, Writing – review & editing

Affiliations Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Department of Microbiology, Immunology & Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

Brett Spear

Roles Conceptualization, Validation, Writing – review & editing

Affiliations Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Department of Microbiology, Immunology & Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

Chunming Liu

Roles Conceptualization, Validation, Writing – review & editing

Affiliations Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America

David S. Watt

Roles Conceptualization, Validation, Writing – review & editing

Affiliations Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America, Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America, Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, Lexington, Kentucky, United States of America

Francesc Marti

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliations Department of Surgery, Transplant Center, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America, Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America

Roberto Gedaly

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

rgeda2@uky.edu

Affiliations Department of Surgery, Transplant Center, College of Medicine, University of Kentucky, Lexington, Kentucky, United States of America, Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America

Competing Interests

CL and DSW have partial ownership in a private venture, Epionc, Inc., incorporated to develop small-molecule inhibitors for cancer treatment through a licensing agreement with the University of Kentucky. In accord with University of Kentucky policies, CL and DSW disclosed prior work to the University of Kentucky’s Intellectual Property Committee and complied with stipulations of the University’s Conflict of Interest Oversight Committee. Epionc, Inc., has no license for compounds described in this paper. This does not alter our adherence to PLOS ONE policies on sharing data and materials.