About the Authors

Qinghai Peng

Roles Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, La Jolla, California, United States of America

Jordan Mechanic

Roles Formal analysis, Investigation, Methodology, Validation

Affiliation Vium Inc., Milpitas, California, United States of America

Ahmed Shoieb

Roles Formal analysis, Investigation, Methodology, Validation

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, Groton, Connecticut, United States of America

Ingrid D. Pardo

Roles Validation

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, Groton, Connecticut, United States of America

Laura Schaevitz

Roles Formal analysis, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Vium Inc., Milpitas, California, United States of America

Judith Fenyk-Melody

Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Comparative Medicine, Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America

Allison Vitsky

Roles Supervision, Validation, Writing – review & editing

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, La Jolla, California, United States of America

Magalie Boucher

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America

Chris Somps

Roles Writing – review & editing

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, Groton, Connecticut, United States of America

Jon C. Cook

Roles Project administration, Supervision, Writing – review & editing

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, Groton, Connecticut, United States of America

Chang-Ning Liu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

chang-ning.liu@pfizer.com

Affiliation Drug Safety Research & Development, Pfizer Worldwide Research & Development, Groton, Connecticut, United States of America

Competing Interests

QP, AS, IP, JF-M, AV, MB, CS, JCC and C-NL are employed by Pfizer. Pfizer paid a scientific service fee to Vium Inc. JM and LS are employed by Vium Inc. There are no patents, products in development or marketed products to declare. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials.