Toll-like receptor 2 confers partial neuroprotection during prion disease

James A. Carroll; Brent Race; Katie Williams; Bruce Chesebro

doi:10.1371/journal.pone.0208559

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Open Access

Peer-reviewed

Research Article

Toll-like receptor 2 confers partial neuroprotection during prion disease

James A. Carroll ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft

* E-mail: carrollja2@niaid.nih.gov

Affiliation Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States of America

http://orcid.org/0000-0003-4329-1488

⨯
Brent Race,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States of America
⨯
Katie Williams,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States of America
⨯
Bruce Chesebro

Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States of America
⨯

Toll-like receptor 2 confers partial neuroprotection during prion disease

James A. Carroll,
Brent Race,
Katie Williams,
Bruce Chesebro

Published: December 31, 2018
https://doi.org/10.1371/journal.pone.0208559

About the Authors

James A. Carroll

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft

* E-mail: carrollja2@niaid.nih.gov

Affiliation Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, United States of America

http://orcid.org/0000-0003-4329-1488

Brent Race

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Katie Williams

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Bruce Chesebro

Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

Competing Interests

The authors have declared that no competing interests exist.

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Animal prion diseases
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Toll-like receptors
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Scrapie
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Complement receptors
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Immune receptor signaling
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Genetically modified animals
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Brain diseases
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Complement system
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