About the Authors

Yutaro Kobayashi

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

kobayashi@shizenmeneki.org

Affiliation Departments of Integrated and Holistic Immunology, Faculty of Medicine, Kagawa University, Kagawa, Japan

Hiroyuki Inagawa

Roles Formal analysis, Funding acquisition, Methodology, Project administration, Resources

Affiliations Departments of Integrated and Holistic Immunology, Faculty of Medicine, Kagawa University, Kagawa, Japan, Control of Innate Immunity, Technology Research Association, Kagawa, Japan, Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan

Chie Kohchi

Roles Resources

Affiliations Departments of Integrated and Holistic Immunology, Faculty of Medicine, Kagawa University, Kagawa, Japan, Macrophi Inc., Kagawa, Japan

Kimiko Kazumura

Roles Resources

Affiliation Central Research Laboratory, Hamamatsu Photonics K.K., Shizuoka, Japan

Hiroshi Tsuchiya

Roles Resources

Affiliation Central Research Laboratory, Hamamatsu Photonics K.K., Shizuoka, Japan

Toshiyuki Miwa

Roles Resources

Affiliation Central Research Laboratory, Hamamatsu Photonics K.K., Shizuoka, Japan

Katsuichiro Okazaki

Roles Conceptualization, Funding acquisition, Resources, Supervision

Affiliation Department of Applied Biological Science, Faculty of Agriculture, Kagawa University, Kagawa, Japan

Gen-Ichiro Soma

Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

Affiliations Departments of Integrated and Holistic Immunology, Faculty of Medicine, Kagawa University, Kagawa, Japan, Control of Innate Immunity, Technology Research Association, Kagawa, Japan, Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan

Competing Interests

CK is employed by Macrophi Inc. KK, HT and TM are employed by Hamamatsu Photonics K.K. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This does not alter our adherence to PLOS ONE policies on sharing data and materials.