About the Authors

Viviana P. Ribeiro

Roles Formal analysis, Investigation, Methodology, Writing – original draft

viviana.ribeiro@dep.uminho.pt

Affiliations 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal, ICVS/3B's – PT Government Associated Laboratory, Braga/Guimarães, Portugal

Joana Silva-Correia

Roles Investigation, Methodology, Writing – review & editing

Affiliations 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal, ICVS/3B's – PT Government Associated Laboratory, Braga/Guimarães, Portugal

Cristiana Gonçalves

Roles Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal, ICVS/3B's – PT Government Associated Laboratory, Braga/Guimarães, Portugal

Sandra Pina

Roles Formal analysis

Affiliations 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal, ICVS/3B's – PT Government Associated Laboratory, Braga/Guimarães, Portugal

Hajer Radhouani

Roles Formal analysis

Affiliations 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal, ICVS/3B's – PT Government Associated Laboratory, Braga/Guimarães, Portugal

Toni Montonen

Roles Formal analysis

Affiliations Computational Biophysics and Imaging Group, ELT Department, Tampere University of Technology, Tampere, Finland, BioMediTech - Institute of Biosciences and Medical Technology, Tampere, Finland

Jari Hyttinen

Roles Supervision

Affiliations Computational Biophysics and Imaging Group, ELT Department, Tampere University of Technology, Tampere, Finland, BioMediTech - Institute of Biosciences and Medical Technology, Tampere, Finland

Anirban Roy

Roles Formal analysis, Writing – review & editing

Affiliation Anasys Instruments Corp - Santa Barbara, California, United States of America

Ana L. Oliveira

Roles Supervision, Writing – review & editing

Affiliation CBQF – Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Porto, Portugal

Rui L. Reis

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliations 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal, ICVS/3B's – PT Government Associated Laboratory, Braga/Guimarães, Portugal, The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal

Joaquim M. Oliveira

Roles Investigation, Methodology, Supervision, Writing – review & editing

Affiliations 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal, ICVS/3B's – PT Government Associated Laboratory, Braga/Guimarães, Portugal, The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Avepark – Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco, Guimarães, Portugal

Competing Interests

The “Anasys Instruments Corp” does not alter our adherence to PLOS ONE policies on sharing data and materials. The authors have declared that no competing interests exist.