Phenyl sulfate, indoxyl sulfate and p-cresyl sulfate decrease glutathione level to render cells vulnerable to oxidative stress in renal tubular cells

Open Access

Peer-reviewed

Research Article

About the Authors

Takeo Edamatsu

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Pharmaceuticals & Agrochemicals Division, Kureha Corporation, Tokyo, Japan

Ayako Fujieda

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Pharmaceuticals & Agrochemicals Division, Kureha Corporation, Tokyo, Japan

Yoshiharu Itoh

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

Affiliation Pharmaceuticals & Agrochemicals Division, Kureha Corporation, Tokyo, Japan

All three authors are employees of Kureha Corporation. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Glutathione
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Hydrogen peroxide
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Sulfates
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Chronic kidney disease
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Oxidative stress
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Cell death
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Antioxidants
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Solutes
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