About the Authors

Christopher D. Johnston

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

cjohnston@forsyth.org

Affiliations Department of Immunology and Infectious Disease, Forsyth Institute, Cambridge, United States of America, Harvard School of Dental Medicine, Boston, MA, United States of America

Chelsey A. Skeete

Roles Investigation, Methodology

Affiliation Department of Immunology and Infectious Disease, Forsyth Institute, Cambridge, United States of America

Alexey Fomenkov

Roles Formal analysis, Investigation, Resources, Software, Validation

Affiliation New England Biolabs, Ipswich, MA, United States of America

Richard J. Roberts

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Resources, Software, Supervision, Writing – review & editing

Affiliation New England Biolabs, Ipswich, MA, United States of America

Susan R. Rittling

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

Affiliations Department of Immunology and Infectious Disease, Forsyth Institute, Cambridge, United States of America, Harvard School of Dental Medicine, Boston, MA, United States of America

Competing Interests

AF and RJR are employees of New England Biolabs, Inc., a company that sells research reagents, including restriction enzymes and DNA methylases to the scientific community. They have no other potential competing commercial interests such as consultancy, patents, products in development or modified products. This employment does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. The other authors declare that they have no other conflicts of interest.