Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases

Marko Novinec

doi:10.1371/journal.pone.0182387

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Open Access

Peer-reviewed

Research Article

Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases

Marko Novinec

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: marko.novinec@fkkt.uni-lj.si

Affiliation Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia

http://orcid.org/0000-0003-1824-1649

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Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases

Marko Novinec

Published: August 3, 2017
https://doi.org/10.1371/journal.pone.0182387

About the Authors

Marko Novinec

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: marko.novinec@fkkt.uni-lj.si

Affiliation Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia

http://orcid.org/0000-0003-1824-1649

Competing Interests

The author has declared that no competing interests exist.

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Proteases
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Molecular dynamics
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Computer software
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Allosteric regulation
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Enzyme structure
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Enzymes
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Principal component analysis
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Sequence alignment
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