About the Authors

Steven R. Pirie-Shepherd

steven.pirie-shepherd@pfizer.com

Affiliation Pfizer Inc, WRD, EORCD, La Jolla, California, United States of America

Cory Painter

Affiliation Pfizer Inc, WRD, EORCD, La Jolla, California, United States of America

Pamela Whalen

Affiliation Pfizer Inc, WRD, EORCD, La Jolla, California, United States of America

Pamela Vizcarra

Affiliation Pfizer Inc, WRD, EORCD, La Jolla, California, United States of America

Marc Roy

Affiliation Pfizer Inc, WRD, IPL, Groton, Connecticut, United States of America

Jesse Qian

Affiliation Pfizer Inc, WRD, IPL, Groton, Connecticut, United States of America

Tania Franks

Affiliation Pfizer Inc, WRD, IPL, Groton, Connecticut, United States of America

Tim Coskran

Affiliation Pfizer Inc, WRD, IPL, Groton, Connecticut, United States of America

Jon Golas

Affiliation Pfizer Inc, WRD, OTTD, Pearl River, New York, United States of America

Shibing Deng

Affiliation Pfizer Inc, WRD, EORCD, La Jolla, California, United States of America

Wenyan Zhong

Affiliation Pfizer Inc, WRD, OTTD, Pearl River, New York, United States of America

Eric Tucker

Affiliation Epic Sciences, San Diego, California, United States of America

Dena Marrinucci

Affiliations Epic Sciences, San Diego, California, United States of America, Truvian Sciences, San Diego, California, United States of America

Hans-Peter Gerber

Current address: Harpoon Therapeutics, Inc, Brisbane, California, United States of America

Affiliation Pfizer Inc, WRD, OTTD, Pearl River, New York, United States of America

Eric L. Powell

Affiliation Pfizer Inc, WRD, EORCD, La Jolla, California, United States of America

Competing Interests

SRPS, PW, PV, MR, JQ, TF, TC, SD, JG, PV, WZ, and ELP are all employees of Pfizer. HPG was an employee of Pfizer when the work was being conducted. ET is an employee of Epic Sciences, DM was an employee of Epic Sciences when the work was being conducted/performed. We can confirm that our conflicting interests section, whereby all the authors are employees or past employees of Pfizer or Epic, does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: SRPS ELP HPG. Data curation: SRPS CP SD. Formal analysis: SRPS SD ELP MR WZ. Funding acquisition: HPG. Investigation: CP PW PV MR JQ TF TC JG ET. Methodology: ELP DM. Project administration: SRPS. Supervision: HPG DM SRPS ELP. Validation: DM SRPS ELP. Visualization: SRPS ET PV. Writing – original draft: SRPS. Writing – review & editing: HPG ELP MR.