About the Authors

Timolaos Rizos

Contributed equally to this work with: Timolaos Rizos, Andreas J. Bartsch

timolaos.rizos@med.uni-heidelberg.de

Affiliation Department of Neurology, University of Heidelberg, Heidelberg, Germany

Andreas J. Bartsch

Contributed equally to this work with: Timolaos Rizos, Andreas J. Bartsch

Affiliations Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany, Oxford Centre for Functional MRI of the Brain, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom, Department of Neuroradiology, University of Würzburg, Würzburg, Germany

Timothy D. Johnson

Affiliation Department of Biostatistics, University of Michigan, Ann Arbor, United States of America

Felix Dittgen

Affiliation Department of Neurology, University of Heidelberg, Heidelberg, Germany

Thomas E. Nichols

Affiliations Oxford Centre for Functional MRI of the Brain, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom, Department of Statistics & Warwick Manufacturing Group, University of Warwick, Coventry, United Kingdom

Uwe Malzahn

Affiliation Clinical Trial Center Würzburg, University Hospital Würzburg, Würzburg, Germany

Roland Veltkamp

Affiliations Department of Neurology, University of Heidelberg, Heidelberg, Germany, Department of Stroke Medicine, Imperial College London, London, United Kingdom

Competing Interests

TR has received consulting honoraria, speakers honoraria and travel support outside this work from BMS Pfizer, Boehringer Ingelheim, Bayer HealthCare and Daiichi Sankyo. AJB has been supported by the German Research Council (Deutsche Forschungsgemeinschaft), the Doppelfeld Foundation and has received travel support from Bayer HealthCare and the International Society for Magnetic Resonance In Medicine (ISMRM). TDJ has been supported in part by NIH Grant 5-R01-NS-075066-05. The work presented in this manuscript represents the views of the authors and not necessarily that of the NIH. Felix Dittgen reports no competing interests. TEN has been supported in part by NIH Grant 5-R01-NS-075066-05, the United Kingdom’s Medical Research Council Grant G0900908 and the Wellcome Trust. The work presented in this manuscript represents the views of the authors and not necessarily that of the NIH, UKMRC or the Wellcome Trust. UM reports no competing interests. RV received consulting honoraria, research support, travel grants, and speakers’ honoraria outside this work from Bayer HealthCare, Boehringer Ingelheim, BMS Pfizer, Daiichi Sankyo, Roche Diagnostics, St. Jude Medical, Apoplexmedical technologies, Medtronic, Sanofi Aventis Morphosys, Amgen and owns Bayer shares. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: TR AJB RV. Data curation: TR AJB TDJ FD TEN RV. Formal analysis: TR AJB TDJ TEN RV. Investigation: TR AJB TDJ FD TEN RV. Methodology: TR AJB TDJ FD TEN UM RV. Project administration: TR AJB RV. Resources: TR AJB TDJ FD TEN RV. Software: AJB DTJ FD TEN. Supervision: TRT AJB RV. Validation: TR AJB TDJ TEN UM RV. Visualization: TR AJB TDJ TEN RV. Writing – original draft: TR AJB RV. Writing – review & editing: TR AJB TDJ FD TEN UM RV.