About the Authors

Takeshi Ikuno

Affiliations Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

Hidetoshi Masumoto

Affiliations Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

Kohei Yamamizu

Affiliation Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Miki Yoshioka

Affiliation Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Kenji Minakata

Affiliation Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

Tadashi Ikeda

Affiliation Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

Ryuzo Sakata

Affiliation Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

Jun K. Yamashita

juny@cira.kyoto-u.ac.jp

Affiliation Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

Competing Interests

JKY is a founder, equity holder, and scientific adviser of iHeart Japan Corporation. JKY, TI and HM are co-inventors on pluripotent stem cell-related patents. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: TI JKY. Data curation: TI. Formal analysis: TI. Funding acquisition: JKY. Investigation: TI KY MY. Methodology: TI HM KY MY JKY. Project administration: JKY HM RS. Resources: TI MY. Supervision: HM KY KM TI RS JKY. Validation: MY. Visualization: TI. Writing – original draft: TI. Writing – review & editing: HM KY JKY.