About the Authors

Kate Birnie

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Alastair D. Hay

Affiliation Centre for Academic Primary Care, NIHR School of Primary Care Research, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Mandy Wootton

Affiliation Specialist Antimicrobial Chemotherapy Unit, Public Health Wales Microbiology Cardiff, University Hospital Wales, Cardiff, United Kingdom

Robin Howe

Affiliation Specialist Antimicrobial Chemotherapy Unit, Public Health Wales Microbiology Cardiff, University Hospital Wales, Cardiff, United Kingdom

Alasdair MacGowan

Affiliation North Bristol NHS Trust, Bristol, United Kingdom

Penny Whiting

Affiliations School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, Kleijnen Systematic Reviews Ltd, York, United Kingdom

Michael Lawton

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Brendan Delaney

Affiliation NIHR Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London, Department of Primary Care and Public Health Sciences, London, United Kingdom

Harriet Downing

Affiliation Centre for Academic Primary Care, NIHR School of Primary Care Research, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Jan Dudley

Affiliation Bristol Royal Hospital for Children, University Hospitals Bristol, NHS Foundation Trust, Bristol, United Kingdom

William Hollingworth

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Catherine Lisles

Affiliation South East Wales Trials Unit (SEWTU), Institute for Translation, Innovation, Methodology and Engagement, School of Medicine, Cardiff University, Cardiff, United Kingdom

Paul Little

Affiliation Primary Care and Population Sciences Division, University of Southampton, Southampton, United Kingdom

Kathryn O’Brien

Affiliation Cochrane Institute of Primary Care & Public Health, School of Medicine, Cardiff University, Cardiff, United Kingdom

Timothy Pickles

Affiliation South East Wales Trials Unit (SEWTU), Institute for Translation, Innovation, Methodology and Engagement, School of Medicine, Cardiff University, Cardiff, United Kingdom

Kate Rumsby

Affiliation Primary Care and Population Sciences Division, University of Southampton, Southampton, United Kingdom

Emma Thomas-Jones

Affiliation South East Wales Trials Unit (SEWTU), Institute for Translation, Innovation, Methodology and Engagement, School of Medicine, Cardiff University, Cardiff, United Kingdom

Judith Van der Voort

Affiliation Department of Paediatrics and Child Health, University Hospital of Wales, Cardiff, United Kingdom

Cherry-Ann Waldron

Affiliation South East Wales Trials Unit (SEWTU), Institute for Translation, Innovation, Methodology and Engagement, School of Medicine, Cardiff University, Cardiff, United Kingdom

Kim Harman

Affiliation Primary Care and Population Sciences Division, University of Southampton, Southampton, United Kingdom

Kerenza Hood

Affiliation South East Wales Trials Unit (SEWTU), Institute for Translation, Innovation, Methodology and Engagement, School of Medicine, Cardiff University, Cardiff, United Kingdom

Christopher C. Butler

Affiliations Cochrane Institute of Primary Care & Public Health, School of Medicine, Cardiff University, Cardiff, United Kingdom, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom

Jonathan A. C. Sterne

jonathan.sterne@bristol.ac.uk

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Competing Interests

None for all except for P. Little who is a member of the NIHR Journals Library Board and has provided consultancy work to Bayer Pharmaceuticals. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: AH CB JS RH MW AM BD K. Hood PL JD WH KOB PW JV. Data curation: HD K. Harman KR ETJ CAW. Formal analysis: KB. Funding acquisition: AH CB JS BD JD WH K. Hood RH PL AM KOB JV PW. Methodology: JS KB AH MW RH AM CB. Supervision: JS AH CB. Writing – original draft: JS KB AH MW RH CB. Writing – review & editing: KB AH MW RH AM PW ML BD HD JD WH CL PL KOB TP KR ETJ JV CAW K. Harman K. Hood CB JS.