About the Authors
- Jacopo Di Gregorio
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Contributed equally to this work with: Jacopo Di Gregorio, Roberta Sferra, Silvia Speca
Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
- Roberta Sferra
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Contributed equally to this work with: Jacopo Di Gregorio, Roberta Sferra, Silvia Speca
Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
- Silvia Speca
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Contributed equally to this work with: Jacopo Di Gregorio, Roberta Sferra, Silvia Speca
Affiliations University of Lille, U995, Lille Inflammation Research International Center (LIRIC), F-59000 Lille, France, IBD, Lille, France
- Antonella Vetuschi
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* E-mail: antonella.vetuschi@univaq.it
Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
- Caroline Dubuquoy
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Affiliation IBD, Lille, France
- Pierre Desreumaux
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Affiliations University of Lille, U995, Lille Inflammation Research International Center (LIRIC), F-59000 Lille, France, IBD, Lille, France, CHR Lille, Service des Maladies de l’Appareil Digestif et de la Nutrition, Hôpital Claude Huriez, Lille, France
- Simona Pompili
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Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
- Loredana Cristiano
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Affiliation Department of Life, Health and Environmental Sciences, University of L'Aquila, L’Aquila, Italy
- Eugenio Gaudio
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Affiliation Department of Human Anatomy, University of Rome La Sapienza, Rome, Italy
- Vincenzo Flati
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¶‡ These authors also contributed equally to this work
Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
- Giovanni Latella
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¶‡ These authors also contributed equally to this work
Affiliation Department of Life, Health and Environmental Sciences, Gastroenterology Unit, University of L'Aquila, L'Aquila, Italy
Competing Interests
Silvia Speca and Caroline Dubuquoy have financial disclosure in the field of PPARγ research with Giuliani SpA. Pierre Desreumaux has the following conflicts of interest for consulting fees, lecture fees or grant supports with Giuliani SpA, Milano, Italy, Procter and Gamble, London, UK, Shire Pharmaceuticals, USA and Lesaffre, Marcq en Baroeul, France. Giovanni Latella has consulted to MSD Italy and Shire; has received research grants from Giuliani Italy, Alfa Wassermann Italy and Sofar Italy. The authors also received funding from Nogra Pharma Ltd and the Intestinal Biotech Development of Lille, France, commercial companies, for this study. GED-0507-34 Levo is a small molecule patented by Nogra Pharma Ltd and in development for the treatment of Ulcerative Colitis. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceptualization: VF GL. Data curation: RS AV SS VF. Formal analysis: RS AV SS SP VF JDG. Funding acquisition: GL VF EG PD. Investigation: RS AV SP SS JDG VF CD. Methodology: RS AV SS JDG VF LC GL. Resources: GL VF. Software: RS AV SS JDG. Supervision: GL VF. Validation: RS AV SS VF. Writing – original draft: RS AV SS JDG VF GL. Writing – review & editing: RS AV SS GL VF.