About the Authors

Bethany Pitcher

Contributed equally to this work with: Bethany Pitcher, Leila Khoja

Affiliation Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

Leila Khoja

Contributed equally to this work with: Bethany Pitcher, Leila Khoja

Affiliation Department of Medical Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

Robert J. Hamilton

Affiliation Department of Urologic Oncology, University Health Network, Toronto, Ontario, Canada

Kald Abdallah

Affiliation Project Data Sphere LLC, Cary, North Carolina, United States of America

Melania Pintilie

Affiliation Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

Anthony M. Joshua

Anthony.joshua@svha.org.au

Affiliations Department of Medical Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada, Department of Medical Oncology, Kinghorn Cancer Centre, St Vincent’s Hospital, Sydney, New South Wales, Australia

Competing Interests

Dr. Joshua has received research funding from Janssen and Astellas. This funding has no relevance to this study. Leila Khoja is an employee of Astrazeneca plc (this work was done independently of AZ). There are no patents, products in development or marketed products to declare. No disclosures to declare by any of the other authors. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: AMJ BP LK RH KA. Data curation: AMJ BP LK. Formal analysis: BP. Investigation: BP LK RH KA MP AMJ. Methodology: BP MP. Project administration: AMJ LK. Resources: KA. Software: BP. Supervision: KA MP AMJ. Validation: BP AMJ. Writing – original draft: BP LK RH KA MP AMJ. Writing – review & editing: BP LK RH KA MP AMJ.