About the Authors

Louise E. Bracken

louise.bracken@alderhey.nhs.uk

Affiliation Paediatric Medicines Research Unit, Institute in the Park, Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom

Anthony J. Nunn

Affiliation Department of Women’s & Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Jamie J. Kirkham

Affiliation Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom

Matthew Peak

Affiliations Paediatric Medicines Research Unit, Institute in the Park, Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom, School of Health, University of Central Lancashire, Preston, United Kingdom

Janine Arnott

Affiliations Paediatric Medicines Research Unit, Institute in the Park, Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom, School of Health, University of Central Lancashire, Preston, Lancashire, United Kingdom

Rosalind L. Smyth

Affiliation Institute of Child Health, University College London, London, United Kingdom

Munir Pirmohamed

Affiliation Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Mark A. Turner

Affiliations Paediatric Medicines Research Unit, Institute in the Park, Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom, Department of Women’s & Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom, Liverpool Women’s NHS Foundation Trust, Liverpool, United Kingdom

Competing Interests

Professor Munir Pirmohamed is a member of the Comission on Human Medicines and Chairs the Pharmacovigilance Expert Advisory Group. Munir Pirmohamed and Professor Rosalind Smyth are NIHR Senior Investigators. This does not alter our adherence to PLOS ONE policies on sharing data and materials. The other authors declare they have no competing interests.

Author Contributions

Formal analysis: LEB JJK MAT. Investigation: LEB AJN M. Pirmohamed MAT. Methodology: LEB AJN JJK M. Pirmohamed MAT RLS JA M. Peak. Visualization: LEB. Writing – original draft: LEB. Writing – review & editing: LEB AJN JJK M. Peak JA RLS M. Pirmohamed MAT.