About the Authors
- Wataru Yamamoto
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* E-mail: w.yamamoto@teijin.co.jp (WY); osada.tomoharu@mg.medience.co.jp (TO)
Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Teijin Pharma Limited, Asahigaoka, Hino-shi, Tokyo, Japan
- Keiichi Asakura
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Nippon Shinyaku Co., Ltd., Nishinosho-monguchi-cho, Kisshoin, Minami-ku, Kyoto, Japan
- Hiroyuki Ando
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Ono Pharmaceutical Co., Ltd., Yamagishi, Mikuni-cho, Sakai-shi, Fukui, Japan
- Tomohiko Taniguchi
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Eisai Co., Ltd., Tokodai, Tsukuba-shi, Ibaraki, Japan
- Atsuko Ojima
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Eisai Co., Ltd., Tokodai, Tsukuba-shi, Ibaraki, Japan
- Takaaki Uda
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Ono Pharmaceutical Co., Ltd., Yamagishi, Mikuni-cho, Sakai-shi, Fukui, Japan
- Tomoharu Osada
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* E-mail: w.yamamoto@teijin.co.jp (WY); osada.tomoharu@mg.medience.co.jp (TO)
Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, LSI Medience Corporation, Uchikanda 1-chome, Chiyoda-ku, Tokyo, Japan
- Seiji Hayashi
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Nippon Shinyaku Co., Ltd., Nishinosho-monguchi-cho, Kisshoin, Minami-ku, Kyoto, Japan
- Chieko Kasai
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Astellas Pharma Inc., Miyukigaoka, Tsukuba-shi, Ibaraki, Japan
- Norimasa Miyamoto
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Eisai Co., Ltd., Tokodai, Tsukuba-shi, Ibaraki, Japan
- Hiroyuki Tashibu
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Ina Research Inc., Nishiminowa, Ina-shi, Nagano, Japan
- Takashi Yoshinaga
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Eisai Co., Ltd., Tokodai, Tsukuba-shi, Ibaraki, Japan
- Daiju Yamazaki
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, National Institute of Health Sciences (NIHS), Kamiyoga, Setagaya-ku, Tokyo, Japan
- Atsushi Sugiyama
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Department of Pharmacology, Faculty of Medicine, Toho University, Omori-Nishi, Ota-ku, Tokyo, Japan
- Yasunari Kanda
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, National Institute of Health Sciences (NIHS), Kamiyoga, Setagaya-ku, Tokyo, Japan
- Kohei Sawada
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, Eisai Co., Ltd., Tokodai, Tsukuba-shi, Ibaraki, Japan
- Yuko Sekino
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Affiliations Japan iPS Cardiac Safety Assessment (JiCSA), Kamiyoga, Setagaya-ku, Tokyo, Japan, Japanese Safety Pharmacology Society (JSPS), Showa-machi, Maebashi, Gunma, Japan, National Institute of Health Sciences (NIHS), Kamiyoga, Setagaya-ku, Tokyo, Japan
Competing Interests
Wataru Yamamoto is employed by Teijin Pharma Limited. Keiichi Asakura and Seiji Hayashi are employed by Nippon Shinyaku Co., Ltd. Hiroyuki Ando and Takaaki Uda are employed by Ono Pharmaceutical Co., Ltd. Tomohiko Taniguchi, Atsuko Ojima, Norimasa Miyamoto, Takashi Yoshinaga and Kohei Sawada are employed by Eisai Co., Ltd. Tomoharu Osada is employed by LSI Medience Corporation. Chieko Kasai is employed by Astellas Pharma Inc. Hiroyuki Tashibu is employed by Ina Research Inc. There are no patents, products in development or marketed products to declare. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceptualization: KS YS. Data curation: WY KA HA TT TO SH CK NM HT TY DY AS YK KS YS. Funding acquisition: YS. Investigation: WY KA HA TT AO TU TO SH CK NM HT TY DY AS YK KS YS. Project administration: YS. Supervision: KS YS. Writing – original draft: WY TO. Writing – review & editing: WY KA HA TT TO SH CK NM HT TY DY AS YK KS YS.