About the Authors

Shoko Iwai

Affiliation Informatics Department, Second Genome Inc., South San Francisco, California, United States of America

Thomas Weinmaier

Affiliation Informatics Department, Second Genome Inc., South San Francisco, California, United States of America

Brian L. Schmidt

Affiliation Bluestone Center for Clinical Research and the Department of Oral and Maxillofacial Surgery, New York University College of Dentistry, New York, New York, United States of America

Donna G. Albertson

Affiliations Bluestone Center for Clinical Research and the Department of Oral and Maxillofacial Surgery, New York University College of Dentistry, New York, New York, United States of America, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America

Neil J. Poloso

Affiliation Research and External Scientific Innovation Department, Allergan PLC, Irvine, California, United States of America

Karim Dabbagh

Affiliation Informatics Department, Second Genome Inc., South San Francisco, California, United States of America

Todd Z. DeSantis

todd@secondgenome.com

Affiliation Informatics Department, Second Genome Inc., South San Francisco, California, United States of America

Competing Interests

This work was supported in part by Second Genome Inc and Allergan PLC. Neil Poloso is employed by Allergen PLC and holds stock options. Shoko Iwai, Thomas Weinmaier, Karim Dabbagh, and Todd DeSantis are employed by Second Genome Inc. and hold stock options. Both Allergan PLC and Second Genome Inc. are independent therapeutics companies with products in development to treat gastrointestinal disorders and other human diseases. A publication announcing the availability of PiPhillin analysis for academic use will not affect the value of our therapeutic products. There are no PiPhillin patents, products in development or marketed products to declare. Second Genome, Inc. provides a commercial microbiome profiling service using software with demonstrable accuracy such as PiPhillin. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceptualization: TD. Data curation: SI TW BS. Formal analysis: SI. Funding acquisition: KD DA NP TD. Investigation: SI BS NP. Methodology: SI. Resources: DA BS NP. Software: SI TW TD. Supervision: TD. Validation: SI. Visualization: SI. Writing – original draft: SI. Writing – review & editing: SI TW TD DA.