About the Authors

Christoph Schliemann

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Joachim Gerss

Affiliation Institute of Biostatistics and Clinical Research, University Hospital Muenster, Muenster, Germany

Stefanie Wiebe

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Jan-Henrik Mikesch

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Nicola Knoblauch

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Tim Sauer

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Linus Angenendt

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Tobias Kewitz

Affiliation Centre for Clinical Trials, University Hospital Muenster, Muenster, Germany

Marc Urban

Affiliation Centre for Clinical Trials, University Hospital Muenster, Muenster, Germany

Trude Butterfass-Bahloul

Affiliation Centre for Clinical Trials, University Hospital Muenster, Muenster, Germany

Sabine Edemir

Current address: Department of Medicine IV, University Hospital Halle, Halle (Saale), Germany

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Kerstin Vehring

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Carsten Müller-Tidow

Current address: Department of Medicine IV, University Hospital Halle, Halle (Saale), Germany

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Wolfgang E. Berdel

Contributed equally to this work with: Wolfgang E. Berdel, Utz Krug

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Utz Krug

Contributed equally to this work with: Wolfgang E. Berdel, Utz Krug

utz.krug@klinikum-lev.de

Current address: Department of Medicine 3, Klinikum Leverkusen, Leverkusen, Germany

Affiliation Department of Medicine A, University Hospital Muenster, Muenster, Germany

Competing Interests

This study was funded by Boehringer Ingelheim Pharma GmbH & Co. KG, which does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Author Contributions

Conceptualization: UK WEB. Formal analysis: JG CS LA TK MU TBB WEB UK. Investigation: CS SW JHM TS CMT WEB UK. Methodology: UK CS WEB. Project administration: NK SE KV WEB UK. Supervision: UK WEB. Writing – original draft: CS WEB UK.