About the Authors

Yoshio Suzuki

yssuzuki@juntendo.ac.jp

Affiliations Graduate School of Health and Sports Science, Juntendo University, Inzai, Chiba, Japan, Faculty of Health and Sports Science, Juntendo University, Inzai, Chiba, Japan

Minoru Fukushima

Affiliations Department of Orthopedic Surgery, School of Medicine, Juntendo University, Tokyo, Japan, Fukushima Orthopedic Clinic, Nasu-Shiobara, Tochigi, Japan

Keishoku Sakuraba

Affiliations Graduate School of Health and Sports Science, Juntendo University, Inzai, Chiba, Japan, Faculty of Health and Sports Science, Juntendo University, Inzai, Chiba, Japan, Department of Orthopedic Surgery, School of Medicine, Juntendo University, Tokyo, Japan

Keisuke Sawaki

Affiliations Graduate School of Health and Sports Science, Juntendo University, Inzai, Chiba, Japan, Faculty of Health and Sports Science, Juntendo University, Inzai, Chiba, Japan

Kazuaki Sekigawa

Affiliation Faculty of Health and Sports Science, Juntendo University, Inzai, Chiba, Japan

Competing Interests

This study was funded by Sunsho Pharmaceutical Co., Ltd. (Fuji, Shizuoka, Japan). This does not alter our adherence to PLOS ONE policies on sharing data and materials. None of the authors was employed by the funder, gave consultancy to the funder, obtained patents with the funder, or developed or marketed products for the funder. This work was also supported by the Grant of Cross-Ministerial Strategic Innovation Promotion Program (SIP). The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YS MF. Performed the experiments: MF. Analyzed the data: YS K. Sekigawa. Wrote the paper: YS K. Sawaki K. Sakuraba.