About the Authors

Scott B. Vafai

svafai@broadinstitute.org (SBV); vamsi@hms.harvard.edu (VKM)

Affiliations Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, United States of America, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Emily Mevers

Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, United States of America

Kathleen W. Higgins

Affiliations Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, United States of America, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Yevgenia Fomina

Affiliations Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, United States of America, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America

Jianming Zhang

Affiliation Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States of America

Anna Mandinova

Affiliation Department of Dermatology, Massachusetts General Hospital, Boston, MA, United States of America

David Newman

Affiliation Natural Products Branch, National Cancer Institute, Frederick, MD, United States of America

Stanley Y. Shaw

Affiliation Center for Systems Biology, Massachusetts General Hospital, Boston, MA, United States of America

Jon Clardy

Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, United States of America

Vamsi K. Mootha

svafai@broadinstitute.org (SBV); vamsi@hms.harvard.edu (VKM)

Affiliations Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, United States of America, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America, Department of Systems Biology, Harvard Medical School, Boston, MA, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: SBV JC VKM. Formal analysis: SBV EM KWH. Funding acquisition: VKM. Investigation: SBV EM KWH YF. Methodology: SBV JC VKM EM. Resources: JZ AM DN SYS. Supervision: SBV VKM JC. Visualization: SBV EM KWH. Writing – original draft: SBV. Writing – review & editing: SBV EM KWH VKM JC SYS DN AM JZ.