About the Authors

Koen M. Marien

koen.marien@uantwerpen.be

Affiliations Division of Physiopharmacology, University of Antwerp, Antwerp, Belgium, HistoGeneX NV, Antwerp, Belgium

Valerie Croons

Affiliation HistoGeneX NV, Antwerp, Belgium

Yannick Waumans

Affiliation HistoGeneX NV, Antwerp, Belgium

Ellen Sluydts

Affiliation HistoGeneX NV, Antwerp, Belgium

Stefanie De Schepper

Affiliation HistoGeneX NV, Antwerp, Belgium

Luc Andries

Affiliation HistoGeneX NV, Antwerp, Belgium

Wim Waelput

Affiliation Department of Pathology, University Hospital Brussels (UZ Brussel), Brussels, Belgium

Erik Fransen

Affiliation StatUa Center for Statistics, University of Antwerp, Antwerp, Belgium

Peter B. Vermeulen

Affiliation CORE (Translational Cancer Research Unit, GZA Hospitals), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium

Mark M. Kockx

Affiliation HistoGeneX NV, Antwerp, Belgium

Guido R. Y. De Meyer

Affiliation Division of Physiopharmacology, University of Antwerp, Antwerp, Belgium

Competing Interests

The authors have read the journal's policy and the authors of this manuscript have the following competing interests: Koen Marien, Valerie Croons, Yannick Waumans, Ellen Sluydts, Stefanie De Schepper, and Luc Andries are employees of HistoGeneX NV (Antwerp, Belgium). Mark Kockx is CEO of HistoGeneX NV, which carries out immunohistochemical testing for pharmaceutical companies as part of (pre-)clinical studies that evaluate new anticancer drugs. Mark Kockx and Wim Waelput are consulting pathologists to Pathomation BVBA. The authors have no other relevant affiliations or financial involvements with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KMM SDS LA PBV MMK GRYDM. Performed the experiments: KMM VC YW ES WW PBV. Analyzed the data: EF YW KM. Contributed reagents/materials/analysis tools: MMK. Wrote the paper: KM YW PBV GRYDM.