About the Authors

Iana H. Haralambieva

Affiliation Mayo Clinic Vaccine Research Group—Department of Medicine, Mayo Clinic and Foundation, Rochester, MN, United States of America

Michael T. Zimmermann

Affiliation Division of Biomedical Statistics and Informatics- Department of Health Science Research, Mayo Clinic and Foundation, Rochester, MN, United States of America

Inna G. Ovsyannikova

Affiliation Mayo Clinic Vaccine Research Group—Department of Medicine, Mayo Clinic and Foundation, Rochester, MN, United States of America

Diane E. Grill

Affiliation Division of Biomedical Statistics and Informatics- Department of Health Science Research, Mayo Clinic and Foundation, Rochester, MN, United States of America

Ann L. Oberg

Affiliation Division of Biomedical Statistics and Informatics- Department of Health Science Research, Mayo Clinic and Foundation, Rochester, MN, United States of America

Richard B. Kennedy

Affiliation Mayo Clinic Vaccine Research Group—Department of Medicine, Mayo Clinic and Foundation, Rochester, MN, United States of America

Gregory A. Poland

poland.gregory@mayo.edu

Affiliation Mayo Clinic Vaccine Research Group—Department of Medicine, Mayo Clinic and Foundation, Rochester, MN, United States of America

Competing Interests

Dr. Poland is the chair of a Safety Evaluation Committee for novel investigational vaccine trials being conducted by Merck Research Laboratories. Dr. Poland offers consultative advice on vaccine development to Merck & Co. Inc., CSL Biotherapies, Avianax, Dynavax, Novartis Vaccines and Therapeutics, Emergent Biosolutions, Adjuvance, Microdermis, Seqirus, NewLink, Protein Sciences, GSK Vaccines, and Sanofi Pasteur. Dr. Poland holds two patents related to vaccinia and measles peptide research. Dr. Kennedy has received funding from Merck Research Laboratories to study waning immunity to mumps vaccine. These activities have been reviewed by the Mayo Clinic Conflict of Interest Review Board and are conducted in compliance with Mayo Clinic Conflict of Interest policies. This research has been reviewed by the Mayo Clinic Conflict of Interest Review Board and was conducted in compliance with Mayo Clinic Conflict of Interest policies. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceptualization: IHH IGO ALO RBK GAP. Data curation: IHH MTZ DEG IGO RBK. Formal analysis: MTZ DEG ALO. Funding acquisition: GAP. Methodology: IHH MTZ IGO DEG ALO RBK. Project administration: GAP. Resources: RBK GAP. Software: MTZ DEG ALO. Supervision: ALO RBK GAP. Visualization: IHH MTZ. Writing - original draft: IHH MTZ DEG IGO ALO RBK. Writing - review & editing: IHH MTZ DEG IGO ALO RBK GAP.