About the Authors

Elliot L. Burghardt

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Katie S. Flenker

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Karen C. Clark

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Jeff Miguel

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Dilek Ince

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Patricia Winokur

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Bradley Ford

Affiliation Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

James O. McNamara II

james-mcnamara@uiowa.edu

Affiliation Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Competing Interests

P.W and D.I. report no conflict of interest. E.L.B., K.S.F., K.C.C. and J.O.M. are inventors on a relevant patent application (“Oligonucleotidebased Probes and Methods for Detection of Microbes”; International Application Number: PCT/US15/15062). B.F. has participated in clinical trials of diagnostic tests with Cepheid Inc and Accelerate Diagnostics Inc. J.O.M. is founder and owner of Nuclease Probe Technologies Inc. These interests do not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ELB KCC DI PW BF JOM. Performed the experiments: ELB KSF KCC JM. Analyzed the data: ELB KSF KCC JM JOM. Wrote the paper: ELB KSF KCC JM DI PW BF JOM.