About the Authors

Stela McLachlan

stela.mclachlan@ed.ac.uk

Affiliation Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom

Claudia Giambartolomei

Affiliation Department of Psychiatry, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, The Leon and Norma Hess Center for Science and Medicine, New York, New York, United States of America

Jon White

Affiliation University College London Genetics Institute, Department of Genetics, Environment and Evolution, London, United Kingdom

Pimphen Charoen

Affiliations Department of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom, Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Andrew Wong

Affiliation MRC Unit for Lifelong Health and Ageing at UCL, London, United Kingdom

Chris Finan

Affiliation Institute of Cardiovascular Science, University College London, London, United Kingdom

Jorgen Engmann

Affiliations Genetic Epidemiology Group, Institute of Cardiovascular Science, University College London, London, United Kingdom, Farr Institute of Health Informatics Research, Department of Epidemiology & Public Health, University College London, London, United Kingdom

Tina Shah

Affiliation Genetic Epidemiology Group, Institute of Cardiovascular Science, University College London, London, United Kingdom

Micha Hersch

Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

Clara Podmore

Affiliation MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, United Kingdom

Alana Cavadino

Affiliations Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom, Population, Policy and Practice, UCL Institute of Child Health, University College London, London, United Kingdom

Barbara J. Jefferis

Affiliation Department of Primary Care & Population Health, UCL Institute of Epidemiology & Health Care, University College London, London, United Kingdom

Caroline E. Dale

Affiliation Farr Institute of Health Informatics Research, Department of Epidemiology & Public Health, University College London, London, United Kingdom

Elina Hypponen

Affiliations Population, Policy and Practice, UCL Institute of Child Health, University College London, London, United Kingdom, Centre for Population Health Research, School of Health Sciences and Sansom Institute of Health Research, University of South Australia, Adelaide, Australia, South Australian Health and Medical Research Institute, Adelaide, Australia

Richard W. Morris

Affiliations Department of Primary Care & Population Health, UCL Institute of Epidemiology & Health Care, University College London, London, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Juan P. Casas

Affiliation Institute of Health Informatics, University College London, London, United Kingdom

Meena Kumari

Affiliations Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom, Department of Epidemiology & Public Health, UCL Institute of Epidemiology & Health Care, University College London, London, United Kingdom

Yoav Ben-Shlomo

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Tom R. Gaunt

Affiliation MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Fotios Drenos

Affiliations MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom

Claudia Langenberg

Affiliations MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, United Kingdom, Institute of Health Informatics, University College London, London, United Kingdom

Diana Kuh

Affiliation MRC Unit for Lifelong Health and Ageing at UCL, London, United Kingdom

Mika Kivimaki

Affiliation Department of Epidemiology & Public Health, UCL Institute of Epidemiology & Health Care, University College London, London, United Kingdom

Rico Rueedi

Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

Gerard Waeber

Affiliation Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

Aroon D. Hingorani

Affiliations Institute of Cardiovascular Science, University College London, London, United Kingdom, Farr Institute of Health Informatics Research, Department of Epidemiology & Public Health, University College London, London, United Kingdom

Jacqueline F. Price

Affiliation Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom

Ann P. Walker

Affiliation Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, United Kingdom

UCLEB Consortium

Membership of the UCLEB Consortium is provided in the Acknowledgments.

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SM. Performed the experiments: SM. Analyzed the data: SM CG JW PC AW CF JE TS MH. Contributed reagents/materials/analysis tools: SM CG JW PC AW CF JE TS RR. Wrote the paper: SM JFP APW CG MH CP BJJ RWM YB-S TRG FD CL M. Kivimaki. Collected and provided data for meta-analysis study: SM AW CP AC BJJ CED EH RWM JPC M. Kumari YB-S TRG FD CL DK M. Kivimaki ADH JFP. Collected and provided data for replication study: CP MH RR GW.