About the Authors

Avi Z. Rosenberg

Contributed equally to this work with: Avi Z. Rosenberg, Matthew Palmer, Lino Merlino

Affiliations Department of Pathology, Children’s National Medical Center, Washington, DC, United States of America, National Institute of Digestive Diseases and Kidney, National Institutes of Health, Bethesda, MD, United States of America

Matthew Palmer

Contributed equally to this work with: Avi Z. Rosenberg, Matthew Palmer, Lino Merlino

Affiliation Department of Pathology, University of Pennsylvania, Philadelphia, PA, United States of America

Lino Merlino

Contributed equally to this work with: Avi Z. Rosenberg, Matthew Palmer, Lino Merlino

Affiliation Department of Pathology, University of Miami, Miami, FL, United States of America

Jonathan P. Troost

Affiliation Department of Pediatrics, Division of Pediatric Nephrology, University of Michigan, Ann Arbor, MI, United States of America

Adil Gasim

Affiliation Department of Pathology, University of North Carolina, Chapel Hill, NC, United States of America

Serena Bagnasco

Affiliation Department of Pathology, The Johns Hopkins School of Medicine, Baltimore, MD, United States of America

Carmen Avila-Casado

Affiliation Department of Pathology, Toronto General Hospital, Toronto, Ontario, Canada

Duncan Johnstone

Affiliation Department of Medicine, Section of Nephrology, Hypertension and Kidney Transplantation Temple University, Philadelphia, PA, United States of America

Jeffrey B. Hodgin

Affiliation Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America

Catherine Conway

Affiliation Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

Brenda W. Gillespie

Affiliation Biostatistics Department, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America

Cynthia C. Nast

Affiliation Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

Laura Barisoni

Affiliation Department of Pathology, University of Miami, Miami, FL, United States of America

Stephen M. Hewitt

genejock@helix.nih.gov

Affiliation Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

Competing Interests

Dr. Laura Barisoni is a consultant for Celgene, Shire and Protalix, a Fabry’s clinical trial utilizing digital pathology. The consultation activities with Protalix are conducted under a contract between the private entity and the University of Miami. Dr. Avi Rosenberg serves on the scientific advisory board for Escala Therapeutics (MaNAC trial). These consultancies do not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AZR MP LM CC DJ CCN LB SMH. Performed the experiments: AZR MP LM AG SB JBH CCN LB CAC. Analyzed the data: BWG JPT. Contributed reagents/materials/analysis tools: CC. Wrote the paper: AZR BWG LB SMH.