Glycogen Repletion in Brown Adipose Tissue upon Refeeding Is Primarily Driven by Phosphorylation-Independent Mechanisms

Christopher M. Carmean; Y. Hanna Huang; Matthew J. Brady

doi:10.1371/journal.pone.0156148

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Peer-reviewed

Research Article

Glycogen Repletion in Brown Adipose Tissue upon Refeeding Is Primarily Driven by Phosphorylation-Independent Mechanisms

Christopher M. Carmean,

Current address: Kobe University Graduate School of Medicine, Department of Molecular and Metabolic Medicine, Kobe, Japan, 650–0047

Affiliation From the Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, Illinois, 60637, United States of America
⨯
Y. Hanna Huang,

Affiliation Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, Illinois, 60637, United States of America
⨯
Matthew J. Brady

* E-mail: mbrady1@uchicago.edu

Affiliations From the Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, Illinois, 60637, United States of America, Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, Illinois, 60637, United States of America
⨯

Glycogen Repletion in Brown Adipose Tissue upon Refeeding Is Primarily Driven by Phosphorylation-Independent Mechanisms

Christopher M. Carmean,
Y. Hanna Huang,
Matthew J. Brady

Published: May 23, 2016
https://doi.org/10.1371/journal.pone.0156148

About the Authors

Christopher M. Carmean

Current address: Kobe University Graduate School of Medicine, Department of Molecular and Metabolic Medicine, Kobe, Japan, 650–0047

Affiliation From the Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, Illinois, 60637, United States of America

Y. Hanna Huang

Affiliation Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, Illinois, 60637, United States of America

Matthew J. Brady

* E-mail: mbrady1@uchicago.edu

Affiliations From the Committee on Molecular Metabolism and Nutrition, University of Chicago, Chicago, Illinois, 60637, United States of America, Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Chicago, Illinois, 60637, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CMC MJB. Performed the experiments: CMC YHH. Analyzed the data: CMC YHH MJB. Contributed reagents/materials/analysis tools: MJB. Wrote the paper: CMC MJB.

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Glycogens
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Phosphorylation
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Enzyme regulation
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Allosteric regulation
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Brown adipose tissue
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Starvation
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Glucose
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Gene expression
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