About the Authors

Tomofumi Fushima

Affiliation Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Sendai, Japan

Akiyo Sekimoto

Affiliation Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Sendai, Japan

Takahiro Minato

Affiliation Advanced Interdisciplinary Biomedical Engineering, Tohoku University Graduate School of Medicine, Sendai, Japan

Takuya Ito

Affiliation Advanced Interdisciplinary Biomedical Engineering, Tohoku University Graduate School of Medicine, Sendai, Japan

Yuji Oe

Affiliation Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

Kiyomi Kisu

Affiliation Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

Emiko Sato

Affiliations Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Sendai, Japan, Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

Kenichi Funamoto

Affiliations Japan Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan, Institute of Fluid Science, Tohoku University, Sendai, Japan

Toshiyuki Hayase

Affiliation Institute of Fluid Science, Tohoku University, Sendai, Japan

Yoshitaka Kimura

Affiliation Advanced Interdisciplinary Biomedical Engineering, Tohoku University Graduate School of Medicine, Sendai, Japan

Sadayoshi Ito

Affiliation Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

Hiroshi Sato

Affiliations Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Sendai, Japan, Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

Nobuyuki Takahashi

ntakaha@m.tohoku.ac.jp

Affiliations Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Sendai, Japan, Division of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NT TF AS TM TI YO. Performed the experiments: TF AS TM TI YO KK ES KF. Analyzed the data: NT TF AS TM TI YO ES. Contributed reagents/materials/analysis tools: NT TF AS TM TI KK ES KF TH YK SI HS. Wrote the paper: NT TF TM TI ES KF TH YK SI HS.