About the Authors

Stefen A. Boehme

sboehme@axikin.com

Affiliation AxikinPharmaceuticals, Inc., San Diego, California, United States of America

Karin Franz-Bacon

Affiliation DNA Consulting, Inc., San Diego, California, United States of America

Danielle N. DiTirro

Current address: Department of Biology, Brandeis University, Waltham, MA, United States of America

Affiliation AxikinPharmaceuticals, Inc., San Diego, California, United States of America

Tai Wei Ly

Affiliation AxikinPharmaceuticals, Inc., San Diego, California, United States of America

Kevin B. Bacon

Affiliation AxikinPharmaceuticals, Inc., San Diego, California, United States of America

Competing Interests

The authors have the following Competing Interests: The authors SAB, DND, TWL, and KBB are presently or were former (DND) employees of Axikin Pharmaceuticals, Inc. KFB is presently an employee of DNA Consulting, Inc. Compound A is listed in the patent entitled “3,5 Diaminopyrazole Kinase Inhibitors”, US Patent number 60/096308. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SAB TWL KBB. Performed the experiments: SAB KFB DND TWL KBB. Analyzed the data: SAB KFB KBB. Wrote the paper: SAB KBB.